Stem Cell Treatment for Stroke is an Option at ASCI
Related Articles Neurotoxicity Associated With Dimethyl Sulfoxide Used in Allogeneic Stem Cell Transplantation. J Pediatr Hematol Oncol. 2017 Jul;39(5):e297-e299 Authors: Ataseven E, Tüfekçi Ö, Yilmaz Ş, Güleryüz H, Ören H Abstract Dimethyl sulfoxide (DMSO) is a cryoprotective agent used in storage of frozen stem cells in stem cell transplantation. Central nervous system side effects of DMSO such as epileptic seizures, stroke, transient global amnesia, and temporary leucoencephalopathy are rarely seen. Here, we report a pediatric patient who developed seizures after DMSO-cryopreserved stem cell infusion and whose magnetic resonance imaging of the brain demonstrated parietal and occipital focal cortical T2-signal intensity increase. DMSO toxicity should be kept in mind in patients who received cryopreserved stem cell infusion and magnetic resonance imaging may be helpful in differential diagnosis of central nervous system involvement. PMID: 28121745 [PubMed - indexed for MEDLINE]Read more...